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Life Science

Functional Genomics Resource Center

Sigma provides functional genomics technologies including RNA interference (RNAi) tools for gene silencing (siRNAesiRNAshRNAmiRNA), cutting-edge systems for gene editing and gene knockout (Sigma CRISPR, CompoZr), and tools for gene expression (LentiORFs). The MISSION® siRNA products offer effective target gene knockdown with reduced off-target effects while the MISSION shRNA portfolio includes the highly validated lentiviral-based shRNA libraries of The RNAi Consortium (TRC1 and TRC2). Revolutionize your research with targeted genome editing using the breakthrough technologies Sigma CRISPR and CompoZr® Zinc Finger Nucleases (ZFN) to add, delete and swap your gene, and TargeTron® gene disruption technology for both eukaryotic and prokaryotic systems.

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