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Molecular Biology

Nucleic Acid Purification

Purify with Sigma

Sigma® Life Science delivers unrivaled quality, expertise and reliability. The GenElute™ portfolio of products includes a variety of kits and reagents for all your nucleic acid purification needs. Whether you are purifying DNA from blood or extracting RNA from fungi, Sigma can help with your experiment.

Plasmid DNA Purification
GenElute™ plasmid kits offer purification of high quality plasmid DNA that is ready for downstream applications including restriction digest, sequencing, cloning and transfection.

Includes kits suitable for:
• Small or large scale plasmid (from
  minipreps to gigapreps)
• Endotoxin-free plasmid
• Vacuum or spin format

Genomic DNA Purification
GenElute™ genomic DNA purification kits provide methods for purifying genomic DNA that eliminate the need for expensive resins and hazardous organic compounds.

Includes kits suitable for:
• Mammalian samples
• Plant samples
• Blood samples
• Gram-negative bacteria
• DNA & RNA co-purification
The Extract-N-Amp™ kits provide all the reagents necessary to rapidly extract and amplify genomic DNA for genotyping. The Extract-N-Amp™ method eliminates the need for homogenization and long enzymatic digestions.

Includes kits suitable for:
• Tissue
• Blood
• Plant
• Seed
RNA Purification
RNA purification kits are simple and cost effective tools for purifying RNA from a variety of samples.

Includes kits suitable for:
• Mammalian total RNA
• Plant total RNA
• mRNA
• microRNA
• DNA & RNA co-purification

Post Reaction
Post reaction purification products allow researchers to quickly and reliably purify amplicons from PCR reactions.

Includes products suitable for:
• PCR Clean-up
• Gel Extraction
Formats include:
• Buffer system kits
• Spin columns
• Pipette tips
Other Reagents & Equipment
Additional reagents are available to assist researchers in the nucleic acid purification.

• RNAlater® for RNA stabilization
• TRI Reagent® for simultaneous
   isolation of RNA, DNA and protein
• Vacuum manifold

High-Throughput Purification
GenElute™ high-throughput purification kits offer significant time-savings through the 96-well format.

Includes kits suitable for:
• Plasmid purification
• Tissue genomic DNA purification
• Blood genomic DNA purification
• Total RNA purification
• PCR clean-up
• Sequencing reaction clean-up
Learning Center
Find all the tools to better understand the DNA & RNA purification products.

Product guides
Literature references

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