SILu™tions – Stable Isotope-labeled MS Internal Standards

What happens when you combine state-of-the-art technology with scientific prowess? Full-length protein standards with the highest purity and isotopic incorporation in the industry. Stable isotope-labeled (SIL) internal standards and high quality calibrations are the essential tools to precisely measure target protein quantitation in mass spectrometry proteomic assays. Our innovative SILutions portfolio meets the needs of different protein quantitation approaches. It’s innovation delivered to you – just right, right now.

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SILuProt (full-length proteins)
• Best MS proteomic internal standards
• Injected into sample before enzymatic
• Cover major human biomarkers
• Unlabeled versions available for use as
  calibrators (SILu™Lite)

• Full-length antibody protein standard
• Highly purified stable isotope-labeled
  universal IgG monoclonal antibody
• Critical tool for pharmacokinetic
  properties of biotherapeutics
• Unlabeled SigmaMAb available for MS
SILuPrEST (50-150 aa)
• Intermediate in length between
  SILuProt and AQUA
• Substantial proteome coverage
• Injected into sample before or after
  enzymatic digestion
• Multiple tryptic peptides per SILuPrEST

AQUA (≤30 aa)
• Accurately quantitate low abundance
• Measure site-specific phosphorylation
• Injected into sample after enzymatic
• Custom synthesis available