The DIG System Highly Sensitive. Short Exposure Times. Safe Handling.

The DIG System is the nonradioactive technology of choice to label and detect nucleic acids for multiple applications. The system is based on a steroid isolated from digitalis plants (Digitalis purpurea and Digitalis lanata). These plants are the only natural source of digoxigenin, so the anti-DIG antibody does not bind to other biological material, ensuring specific labeling.


Use robust procedures and established protocols for straightforward, sensitive, and efficient nonradioactive labeling and detection.


Hybridized DIG-labeled probes may be detected with high affinity anti-digoxigenin (anti-DIG) antibodies that are coupled to either alkaline phosphatase (AP), horseradish peroxidase (POD), or fluorescein and rhodamine for colorimetric, chemiluminescent, or fluorescent detection.

Need help? Check out our DIG product selection guide:

For more information, see the following brochures:

Detailed technical information can be found in the DIG Manuals:

Learn how to handle the DIG System in our Technical Tips:

DIG is a trademark of Roche
For life science research only. Not for use in diagnostic procedures