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Functionalized Silica Gel Scavengers

Chemfiles Volume 3 Article 5

Sigma-Aldrich Corporation and SiliCycle Inc. have collaborated to offer scientists ultra pure functionalized silica gels for medicinal and parallel chemistry. These silica gels offer several advantages over traditional polystyrene based products:

  • Broad solvent compatibility, including polar solvents
  • Minimal swelling, which facilitates the use in automated flow-through systems
  • Ease of handling, since they develop no static charge; this simplifies filling cartridges and columns
  • Thermal stability, which allows their use in microwave-assisted reactions

Highlighted below are the functionalized silica gels that can be utilized as scavengers in organic synthesis. For a complete listing of all of SiliCycle’s products offered by Sigma-Aldrich, please email

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