Technical Webinar

Advanced 3D Cell Culture Models


Stefan Przyborski, PhD, Professor of Cell Technology, Durham University UK
Jim Cooper, Cell Biology Applications Scientist, Public Health England

Date and time:  June 12th (14:00 BST / 15:00 CEST / 08:00 CDT)

As 3D cell culture technology becomes established and accepted as a means of creating more physiologically relevant cell-based assays, methods that recreate the organized structure of real tissues will become valuable research tools for use in discovery, validation studies and for modelling disease. Tissues in the body are mostly composed of different cell types that are often highly organized in relation to each other. Often cells are arranged in distinct layers that enable signalling and cell-to-cell interactions. Alternatively in tumours, cancer cells form aggregates and tissue masses composed of different cell types. There is no one technology that satisfies all applications.

This webinar will review the alternative approaches available to researchers and provide an overview of their potential along with example applications.

Topics covered:

  • Aggregate-based methods; hydrogels and extra-cellular matrices and inert scaffold-based technologies.
  • Their strengths and weaknesses for different applications.
  • Evolution of 3D cell culture to a new level where real tissue-like structures can be generated
    in vitro.

Speaker biography:

Stefan Przyborski, PhD, Professor of Cell Technology, Durham University UK

Stefan holds an academic position as Professor in Cell Technology at Durham University. He has over 25 years’ experience in cell biology with specific interests in cell culture technology, neuroscience and stem cell research. In recent years he has developed a multi-disciplinary approach to develop novel ways of solving biological problems. In regard to cell technology, he is involved with the research, development and commercialization of technology to enhance the environment in which cells are cultured, to improve their growth, differentiation and function. He is a recognized leader in the area of three dimensional (3D) cell culture and frequently contributes to inter/national meetings on this topic. His first degree in anatomy and cell biology still to this day underpins his strong belief in the fundamental principle of how the structure is related to function at the cell and tissue level. This is a critical aspect in cell culture where changes to cell shape radically impact cell behaviour, which plays a major role in 3D cell culture.

Jim Cooper, Cell Biology Applications Scientist, ECACC

Jim has over 20 years experience of delivering authentic cell cultures for researchers in academia and industry and has a wide and deep knowledge of cell biology applications. He's played a key role at ECACC managing internal and external projects and developing ECACC's cell culture training courses.  As a member of the International Cell Line Authentication Committee (ICLAC) he has a growing reputation as an enthusiastic speaker, delivering many seminars on good cell culture practice to Institutes and companies across Europe.