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Tumour Spheroid

Submitted by: Ms. Isabell Smyrek
Johann Wolfgang Goethe-Universität Frankfurt am Main

A multicellular tumor spheroid (MCTS) composed of U343 glioblastoma cells was PFA-fixed, paraffin embedded and sectioned. b-catenin (magenta) and a-tubulin (yellow) antibodies as well as DAPI (cyan) to stain cell nuclei were used. The magnified area highlights cell division. The spindle apparatus formed from microtubules (yellow) tears the chromatides (cyan) apart.

Magnification: 40x



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