NR1H4
nuclear receptor subfamily 1, group H, member 4
Synonyms:
BAR, FXR, HRR-1, HRR1, RIP14
Species:
Human NR1H4 (9971), Mouse Nr1h4 (20186), Rat Nr1h4 (60351), domestic cat NR1H4 (101096997), naked mole-rat Nr1h4 (101714263), cow NR1H4 (540528), domestic guinea pig Nr1h4 (100734377), Zebrafish nr1h4 (436847), Horse NR1H4 (100052821), chicken NR1H4 (373902) ...More
UniProtKB ID:
Gene ID:
- Human(9971) Summary: This gene encodes a ligand-activated transcription factor, which shares structural features in common with nuclear hormone receptor family, such as a DNA-binding domain that targets the receptor to specific DNA sequences, and a ligand-binding domain, which interacts directly with the ligand and contains a ligand-dependent transcriptional activation domain. This protein functions as a receptor for bile acids, and when bound to bile acids, regulates the expression of genes involved in bile acid synthesis and transport. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
- Mouse(20186) nuclear receptor subfamily 1, group H, member 4
- Rat(60351) nuclear receptor subfamily 1, group H, member 4
- domestic cat(101096997) nuclear receptor subfamily 1, group H, member 4
- naked mole-rat(101714263) nuclear receptor subfamily 1, group H, member 4
- cow(540528) nuclear receptor subfamily 1, group H, member 4
- domestic guinea pig(100734377) nuclear receptor subfamily 1, group H, member 4
- Zebrafish(436847) nuclear receptor subfamily 1, group H, member 4
- Horse(100052821) nuclear receptor subfamily 1, group H, member 4
- chicken(373902) nuclear receptor subfamily 1, group H, member 4
- dog(612928) nuclear receptor subfamily 1, group H, member 4
- sheep(101105401) nuclear receptor subfamily 1, group H, member 4
- Domestic Rabbit(100009485) nuclear receptor subfamily 1, group H, member 4
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Small Molecule - Agonist
Product Number
Description
Species
Ursodeoxycholic acid for system suitability, European Pharmacopoeia (EP) Reference Standard,
Species
human