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Merck

AIFM1

apoptosis-inducing factor, mitochondrion-associated, 1

Synonimy:
AIF, CMTX4, COWCK, COXPD6, PDCD8
Gatunek:
Human AIFM1 (9131), Mouse Aifm1 (26926), Rat Aifm1 (83533), Horse AIFM1 (100054546), cow AIFM1 (535714), sheep AIFM1 (100188912), sheep AIFM1 (101121574), Zebrafish aifm1 (373125), chicken AIFM1 (428688), domestic cat AIFM1 (768258) ...Więcej
Identyfikator UniProtKB:
O95831, A4QPB4, B1ALN1, B2RB08, D3DTE9, Q1L6K4, Q1L6K6, Q2QKE4
Identyfikator genu:
  • Human(9131) Summary: This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10. [provided by RefSeq, May 2010]
  • Mouse(26926) apoptosis-inducing factor, mitochondrion-associated 1
  • Rat(83533) apoptosis-inducing factor, mitochondrion-associated 1
  • Horse(100054546) apoptosis-inducing factor, mitochondrion-associated, 1
  • cow(535714) apoptosis-inducing factor, mitochondrion-associated, 1
  • sheep(100188912) apoptosis-inducing factor, mitochondrion-associated, 1
  • sheep(101121574) apoptosis-inducing factor, mitochondrion-associated, 1
  • Zebrafish(373125) apoptosis-inducing factor, mitochondrion-associated 1
  • chicken(428688) apoptosis-inducing factor, mitochondrion-associated, 1
  • domestic cat(768258) apoptosis-inducing factor, mitochondrion-associated, 1
  • domestic guinea pig(100730787) apoptosis-inducing factor, mitochondrion-associated, 1
  • naked mole-rat(101698690) apoptosis-inducing factor, mitochondrion-associated, 1
  • Domestic Rabbit(100347778) apoptosis-inducing factor, mitochondrion-associated, 1
  • dog(481048) apoptosis-inducing factor, mitochondrion-associated, 1

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB5700185
Przeciwciało anty-AIFprodukowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB5701260
Anty-AIF, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
AB16502
Anti-AIF Antibody, NT, Chemicon®, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
western blot
HPA030611
Anti-AIFM1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
07-208
Przeciwciało anty-AIF (czynnik indukujący apoptozę), Upstate®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

esiRNA

Numer produktu
Opis
Gatunek
EHU079251
MISSION® esiRNA, targeting human AIFM1,
Gatunek
human
EMU032921
MISSION® esiRNA, targeting mouse Aifm1,
Gatunek
mouse