AIRE
autoimmune regulator
Synonyme:
AIRE1, APECED, APS1, APSI, PGA1
Spezies:
Human AIRE (326), Mouse Aire (11634), Rat Aire (294328), domestic guinea pig Aire (100729880), sheep AIRE (101102698), cow AIRE (784775), Zebrafish aire (100007662), chicken AIRE (429666), dog AIRE (487796), naked mole-rat Aire (101725873)
UniProtKB-ID:
Gen-ID:
- Human(326) Summary: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
- Mouse(11634) autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
- Rat(294328) autoimmune regulator
- domestic guinea pig(100729880) autoimmune regulator
- sheep(101102698) autoimmune regulator
- cow(784775) autoimmune regulator
- Zebrafish(100007662) autoimmune regulator
- chicken(429666) autoimmune regulator
- dog(487796) autoimmune regulator
- naked mole-rat(101725873) autoimmune regulator
- domestic cat(101091039) autoimmune regulator
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-AIRE Antibody, clone Mab155, clone Mab155, 1 mg/mL, from mouse,
Speziesreaktivität
human
Anwendung
flow cytometry
immunocytochemistry
western blot
immunocytochemistry
western blot
Anti-AIRE (Isoforms 1 and 2) (AB2) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Speziesreaktivität
human
Anwendung
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot