AKR1D1
aldo-keto reductase family 1, member D1
Synonyms:
3o5bred, CBAS2, SRD5B1
Species:
Human AKR1D1 (6718), Mouse Akr1d1 (208665), Rat Akr1d1 (192242), cow AKR1D1 (513855), Domestic Rabbit AKR1D1 (100008612), sheep AKR1D1 (101103641), domestic cat AKR1D1 (101100551), chicken AKR1D1 (418107), domestic guinea pig Akr1d1 (100713034), dog AKR1D1 (482711) ...More
UniProtKB ID:
Gene ID:
- Human(6718) Summary: The enzyme encoded by this gene is responsible for the catalysis of the 5-beta-reduction of bile acid intermediates and steroid hormones carrying a delta(4)-3-one structure. Deficiency of this enzyme may contribute to hepatic dysfunction. Three transcript variants encoding different isoforms have been found for this gene. Other variants may be present, but their full-length natures have not been determined yet. [provided by RefSeq, Jul 2010]
- Mouse(208665) aldo-keto reductase family 1, member D1
- Rat(192242) aldo-keto reductase family 1, member D1
- cow(513855) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
- Domestic Rabbit(100008612) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
- sheep(101103641) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
- domestic cat(101100551) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
- chicken(418107) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
- domestic guinea pig(100713034) aldo-keto reductase family 1, member D1
- dog(482711) aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
- dog(491379) 3-oxo-5-beta-steroid 4-dehydrogenase-like
- naked mole-rat(101716388) aldo-keto reductase family 1, member D1
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