ALDH1A2
aldehyde dehydrogenase 1 family, member A2
Synonyms:
RALDH(II), RALDH2, RALDH2-T
Species:
Human ALDH1A2 (8854), Mouse Aldh1a2 (19378), Rat Aldh1a2 (116676), naked mole-rat Aldh1a2 (101699741), domestic guinea pig Aldh1a2 (100718164), dog ALDH1A2 (478319), sheep ALDH1A2 (101117509), chicken ALDH1A2 (395844), Zebrafish aldh1a2 (116713), Domestic Rabbit ALDH1A2 (100339014) ...More
UniProtKB ID:
Gene ID:
- Human(8854) Summary: This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, May 2011]
- Mouse(19378) aldehyde dehydrogenase family 1, subfamily A2
- Rat(116676) aldehyde dehydrogenase 1 family, member A2
- naked mole-rat(101699741) aldehyde dehydrogenase 1 family, member A2
- domestic guinea pig(100718164) aldehyde dehydrogenase 1 family, member A2
- dog(478319) aldehyde dehydrogenase 1 family, member A2
- sheep(101117509) aldehyde dehydrogenase 1 family, member A2
- chicken(395844) aldehyde dehydrogenase 1 family, member A2
- Zebrafish(116713) aldehyde dehydrogenase 1 family, member A2
- Domestic Rabbit(100339014) aldehyde dehydrogenase 1 family, member A2
- domestic cat(101082916) aldehyde dehydrogenase 1 family, member A2
- cow(535075) aldehyde dehydrogenase 1 family, member A2
- Horse(100054550) aldehyde dehydrogenase 1 family, member A2
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