ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
Synonyme:
GEF3, STA3, XPLN
Spezies:
Human ARHGEF3 (50650), Mouse Arhgef3 (71704), Rat Arhgef3 (290541), Domestic Rabbit ARHGEF3 (100352585), Zebrafish arhgef3 (570228), chicken ARHGEF3 (416000), dog ARHGEF3 (476579), domestic guinea pig Arhgef3 (100725004), naked mole-rat Arhgef3 (101705127), domestic cat ARHGEF3 (101096044) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(50650) Summary: Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(71704) Rho guanine nucleotide exchange factor (GEF) 3
- Rat(290541) Rho guanine nucleotide exchange factor (GEF) 3
- Domestic Rabbit(100352585) Rho guanine nucleotide exchange factor (GEF) 3
- Zebrafish(570228) Rho guanine nucleotide exchange factor (GEF) 3
- chicken(416000) Rho guanine nucleotide exchange factor (GEF) 3
- dog(476579) Rho guanine nucleotide exchange factor (GEF) 3
- domestic guinea pig(100725004) Rho guanine nucleotide exchange factor (GEF) 3
- naked mole-rat(101705127) Rho guanine nucleotide exchange factor (GEF) 3
- domestic cat(101096044) Rho guanine nucleotide exchange factor (GEF) 3
- cow(782247) Rho guanine nucleotide exchange factor (GEF) 3
- Horse(100051041) Rho guanine nucleotide exchange factor (GEF) 3
- sheep(101103763) Rho guanine nucleotide exchange factor (GEF) 3
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-ARHGEF3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot
Anti-ARHGEF3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Speziesreaktivität
human
Anwendung
immunofluorescence