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Merck

ASAH1

N-acylsphingosine amidohydrolase (acid ceramidase) 1

Sinónimos:
AC, ACDase, ASAH, PHP, PHP32, SMAPME
Especie:
Human ASAH1 (427), Mouse Asah1 (11886), Rat Asah1 (84431), sheep ASAH1 (101117904), domestic cat ASAH1 (101082231), cow ASAH1 (510620), chicken ASAH1 (422727), naked mole-rat Asah1 (101724913), dog ASAH1 (482897), domestic guinea pig Asah1 (100735549)
ID UniProtKB:
Q13510, E9PDS0, Q6W898, Q96AS2
ID del gen:
  • Human(427) Summary: This gene encodes a heterodimeric protein consisting of a nonglycosylated alpha subunit and a glycosylated beta subunit that is cleaved to the mature enzyme posttranslationally. The encoded protein catalyzes the synthesis and degradation of ceramide into sphingosine and fatty acid. Mutations in this gene have been associated with a lysosomal storage disorder known as Farber disease. Multiple transcript variants encoding several distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11886) N-acylsphingosine amidohydrolase 1
  • Rat(84431) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • sheep(101117904) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • domestic cat(101082231) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • cow(510620) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • chicken(422727) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • naked mole-rat(101724913) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • dog(482897) N-acylsphingosine amidohydrolase (acid ceramidase) 1
  • domestic guinea pig(100735549) N-acylsphingosine amidohydrolase (acid ceramidase) 1

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Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
ABN468
Anti-ASAH1 Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human, mouse
Aplicación
immunofluorescence
immunohistochemistry
western blot

esiRNA

Número de producto
Descripción
Especie
EHU064111
MISSION® esiRNA, targeting human ASAH1,
Especie
human