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AXL

AXL receptor tyrosine kinase

Synonyms:
JTK11, UFO
Species:
UniProtKB ID:
Gene ID:
  • Human(558) Summary: The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
  • Mouse(26362) AXL receptor tyrosine kinase
  • Rat(308444) Axl receptor tyrosine kinase
  • Horse(100064907) AXL receptor tyrosine kinase
  • naked mole-rat(101701026) AXL receptor tyrosine kinase
  • dog(484490) AXL receptor tyrosine kinase
  • domestic cat(101086688) AXL receptor tyrosine kinase
  • Thale Cress(817802) AXR1-like protein
  • domestic guinea pig(100729961) AXL receptor tyrosine kinase
  • cow(516598) AXL receptor tyrosine kinase
  • sheep(101102750) AXL receptor tyrosine kinase

Custom & Knockdown Gene Products

ELISA

Product Number
Description
Species
Human Axl ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Phosphotyrosine AXL / Tyrosine-protein Kinase Receptor UFO ELISA Kit, ,
Species
human
Mouse Axl ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-AXL antibody produced in mouse, clone 7E10, ascites fluid,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-Axl Antibody, clone 3D13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, monkey, mouse
Application
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Monoclonal Anti-AXL antibody produced in mouse, clone 6C8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
Anti-phospho-AXL (pTyr698) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot
Anti-AXL antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
Axl Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant amino acids 473-end human Axl, for use in Kinase Assays.,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human AXL,
Species
human
MISSION® esiRNA, targeting mouse Axl,
Species
mouse

Small Molecule - Substrate

Product Number
Description
Species
Axltide, ,
Species
human