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Merck

CHRNB3

cholinergic receptor, nicotinic, beta 3 (neuronal)

Sinónimos:
Especie:
ID UniProtKB:
ID del gen:
  • Human(1142) Summary: The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are (hetero)pentamers composed of homologous subunits. The subunits that make up the muscle and neuronal forms of nAChRs are encoded by separate genes and have different primary structure. There are several subtypes of neuronal nAChRs that vary based on which homologous subunits are arranged around the central channel. They are classified as alpha-subunits if, like muscle alpha-1 (MIM 100690), they have a pair of adjacent cysteines as part of the presumed acetylcholine binding site. Subunits lacking these cysteine residues are classified as beta-subunits (Groot Kormelink and Luyten, 1997 [PubMed 9009220]
  • Mouse(108043) cholinergic receptor, nicotinic, beta polypeptide 3
  • Rat(171131) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • domestic cat(101098624) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • cow(521702) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • Domestic Rabbit(100355898) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • sheep(101122833) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • chicken(395604) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • dog(482837) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • naked mole-rat(101706291) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • domestic guinea pig(100723424) cholinergic receptor, nicotinic, beta 3 (neuronal)
  • Horse(100054095) cholinergic receptor, nicotinic, beta 3 (neuronal)

Custom & Knockdown Gene Products

Small Molecule - Agonist

Número de producto
Descripción
Especie
Decamethonium bromide, crystalline,
Especie
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Especie
human, rat

Small Molecule - Antagonist

Número de producto
Descripción
Especie
Mecamylamine hydrochloride, ,
Especie
human
1,1-Dimethyl-4-phenylpiperazinium iodide, ≥98% (TLC or titration),
Especie
human, rat
Kynurenic acid, ≥98%,
Especie
rat, human

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-CHRNB3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry

Small Molecule - Blocker

Número de producto
Descripción
Especie
Tetraethylammonium chloride, ≥98% (titration),
Especie
human
Hexamethonium bromide, ,
Especie
human
Hexamethonium chloride, solid (hygroscopic),
Especie
human
Kynurenic acid, ≥98%,
Especie
rat, human

Proteins

Número de producto
Descripción
Especie
Buserelin acetate salt, ≥90% (HPLC),
Especie
rat