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Merck

CXCR4

chemokine (C-X-C motif) receptor 4

Synonyms:
CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Species:
UniProtKB ID:
Gene ID:
  • Human(7852) Summary: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(12767) chemokine (C-X-C motif) receptor 4
  • Rat(60628) chemokine (C-X-C motif) receptor 4
  • cow(281736) chemokine (C-X-C motif) receptor 4
  • domestic guinea pig(100731341) chemokine (C-X-C motif) receptor 4
  • dog(483900) chemokine (C-X-C motif) receptor 4
  • naked mole-rat(101699254) chemokine (C-X-C motif) receptor 4
  • sheep(443532) neuropeptide Y receptor type 3
  • chicken(395324) chemokine (C-X-C motif) receptor 4
  • Domestic Rabbit(100346189) chemokine (C-X-C motif) receptor 4
  • domestic cat(493676) chemokine (C-X-C motif) receptor 4

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-phospho-CXCR4 (pSer339) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-CXCR4 (Fusin) (182-196) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CXCR4 antibody produced in mouse, clone 1F8, ascites fluid,
Species Reactivity
human
Application
ELISA
western blot
Anti-Human CXCR4/CD184 (12G5) ColorWheel® Dye-Ready mAb, ,
Species Reactivity
human
Application
flow cytometry
Anti-CXCR4 antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human CXCR4,
Species
human