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CXCR4

chemokine (C-X-C motif) receptor 4

Synonyme:
CD184, D2S201E, FB22, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(7852) Summary: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(12767) chemokine (C-X-C motif) receptor 4
  • Rat(60628) chemokine (C-X-C motif) receptor 4
  • cow(281736) chemokine (C-X-C motif) receptor 4
  • domestic guinea pig(100731341) chemokine (C-X-C motif) receptor 4
  • dog(483900) chemokine (C-X-C motif) receptor 4
  • naked mole-rat(101699254) chemokine (C-X-C motif) receptor 4
  • sheep(443532) neuropeptide Y receptor type 3
  • chicken(395324) chemokine (C-X-C motif) receptor 4
  • Domestic Rabbit(100346189) chemokine (C-X-C motif) receptor 4
  • domestic cat(493676) chemokine (C-X-C motif) receptor 4

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-CXCR4 Antibody, clone 12G5, clone 12G5, from mouse,
Speziesreaktivität
human
Anwendung
flow cytometry
immunocytochemistry

neutralization
Monoclonal Anti-CXCR4 antibody produced in mouse, clone 1F8, ascites fluid,
Speziesreaktivität
human
Anwendung
ELISA
western blot
Anti-CXCR4 antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Speziesreaktivität
human, mouse
Anwendung
ELISA
flow cytometry

immunocytochemistry

immunofluorescence

immunoprecipitation (IP)

western blot
Anti-CXCR4 Antibody, clone 2L2, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Speziesreaktivität
human
Anwendung
ELISA
affinity binding assay

immunocytochemistry

immunohistochemistry
Monoclonal Anti-CXCR4, (N-terminal) antibody produced in mouse, clone 2G9, purified immunoglobulin, buffered aqueous solution,
Speziesreaktivität
human, rat
Anwendung
ELISA
western blot

Proteins

Produktnummer
Beschreibung
Spezies
ChemiSCREEN CXCR4 Membrane Preparation, Human CXCR4 GPCR membrane preparation for Radioligand binding Assays & GTPgammaS binding.,
Spezies
human

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human CXCR4,
Spezies
human
MISSION® esiRNA, targeting mouse Cxcr4,
Spezies
mouse