CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
别名:
CPT7, CYP17, P450C17, S17AH
物种:
Human CYP17A1 (1586), Mouse Cyp17a1 (13074), Rat Cyp17a1 (25146), Horse CYP17A1 (100034232), Zebrafish cyp17a1 (399692), cow CYP17A1 (281739), sheep CYP17A1 (493968), domestic cat CYP17A1 (493967), chicken CYP17A1 (425056), dog CYP17A1 (477807)
UniProtKB ID:
基因ID:
- Human(1586) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008]
- Mouse(13074) cytochrome P450, family 17, subfamily a, polypeptide 1
- Rat(25146) cytochrome P450, family 17, subfamily a, polypeptide 1
- Horse(100034232) cytochrome P-450 17 alpha-hydroxylase/C17,20-lyase
- Zebrafish(399692) cytochrome P450, family 17, subfamily A, polypeptide 1
- cow(281739) cytochrome P450, family 17, subfamily A, polypeptide 1
- sheep(493968) cytochrome P450, family 17, subfamily A, polypeptide 1
- domestic cat(493967) cytochrome P450, family 17, subfamily A, polypeptide 1
- chicken(425056) cytochrome P450, family 17, subfamily A, polypeptide 1
- dog(477807) cytochrome P450, family 17, subfamily A, polypeptide 1
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