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Merck

CYP26A1

cytochrome P450, family 26, subfamily A, polypeptide 1

Sinonimi:
CP26, CYP26, P450RAI, P450RAI1
Specie:
ID UniProtKB:
ID gene:
  • Human(1592) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(13082) cytochrome P450, family 26, subfamily a, polypeptide 1
  • Rat(154985) cytochrome P450, family 26, subfamily a, polypeptide 1
  • Zebrafish(30381) cytochrome P450, subfamily XXVIA, polypeptide 1
  • cow(539047) cytochrome P450, family 26, subfamily A, polypeptide 1
  • chicken(408183) cytochrome P450, family 26, subfamily A, polypeptide 1
  • dog(486804) cytochrome P450, family 26, subfamily A, polypeptide 1

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-CYP26A1 antibody produced in rabbit, ,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Anti-CYP26A1 (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Ketoconazole, 99.0-101.0% (EP, titration), meets EP testing specifications,
Specie
mouse, human, rat

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human CYP26A1,
Specie
human
MISSION® esiRNA, targeting mouse Cyp26a1,
Specie
mouse