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DENND1B

DENN/MADD domain containing 1B

Synonimy:
C1ORF18, C1orf218, FAM31B
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(163486) Summary: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]
  • Mouse(329260) DENN/MADD domain containing 1B
  • Rat(289051) DENN/MADD domain containing 1B
  • Horse(100061134) DENN/MADD domain containing 1B
  • domestic cat(101096630) DENN/MADD domain containing 1B
  • naked mole-rat(101713291) DENN/MADD domain containing 1B
  • dog(490259) DENN/MADD domain containing 1B
  • chicken(424351) DENN/MADD domain containing 1B
  • Zebrafish(560720) DENN/MADD domain containing 1B
  • cow(515939) DENN/MADD domain containing 1B

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-DENND1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human DENND1B,
Gatunek
human