GADD45B
growth arrest and DNA-damage-inducible, beta
同義詞:
GADD45BETA, MYD118
物種:
Human GADD45B (4616), Mouse Gadd45b (17873), Rat Gadd45b (299626), naked mole-rat Gadd45b (101710909), domestic guinea pig Gadd45b (100730773), sheep GADD45B (101120573), cow GADD45B (618405), domestic cat GADD45B (101087971), dog GADD45B (485069), chicken GADD45B (429929)
UniProtKB ID:
基因 ID:
- Human(4616) Summary: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008]
- Mouse(17873) growth arrest and DNA-damage-inducible 45 beta
- Rat(299626) growth arrest and DNA-damage-inducible, beta
- naked mole-rat(101710909) growth arrest and DNA-damage-inducible, beta
- domestic guinea pig(100730773) growth arrest and DNA-damage-inducible, beta
- sheep(101120573) growth arrest and DNA-damage-inducible, beta
- cow(618405) growth arrest and DNA-damage-inducible, beta
- domestic cat(101087971) growth arrest and DNA-damage-inducible, beta
- dog(485069) growth arrest and DNA-damage-inducible, beta
- chicken(429929) growth arrest and DNA-damage-inducible, beta
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