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Merck

GHR

growth hormone receptor

Sinonimi:
GHBP
Specie:
ID UniProtKB:
ID gene:
  • Human(2690) Summary: This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
  • Mouse(14600) growth hormone receptor
  • Rat(25235) growth hormone receptor
  • dog(403721) growth hormone receptor
  • chicken(408184) growth hormone receptor
  • naked mole-rat(101716037) growth hormone receptor
  • domestic guinea pig(100135527) growth hormone receptor
  • Domestic Rabbit(100009325) growth hormone receptor
  • sheep(443333) growth hormone receptor
  • Goat(100860790) growth hormone receptor
  • cow(280805) growth hormone receptor
  • domestic cat(101093244) growth hormone receptor

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human GHR ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-Growth Hormone Receptor antibody produced in goat, affinity isolated antibody, lyophilized powder,
Reattività con
mouse
Applicazione
immunohistochemistry
western blot
Anti-GHR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
Anti-GHR Mouse mAb (3A12), liquid, clone 3A12, Calbiochem®,
Reattività con
human
Applicazione
Anti-GHR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunofluorescence
Anti-GHR antibody produced in rabbit, affinity isolated antibody,
Reattività con
human
Applicazione
western blot

Small Molecule - Ligand

Numero di prodotto
Descrizione
Specie
Somatotropin from human pituitary, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder,
Specie
human

Proteins

Numero di prodotto
Descrizione
Specie
Somatotropin from human pituitary, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder,
Specie
human

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human GHR,
Specie
human
MISSION® esiRNA, targeting mouse Ghr,
Specie
mouse