HIRA
histone cell cycle regulator
Synonimy:
DGCR1, TUP1, TUPLE1
Gatunek:
Human HIRA (7290), Mouse Hira (15260), Rat Hira (363849), Thale Cress HIRA (823578), Domestic Rabbit HIRA (100352472), sheep HIRA (101120607), cow HIRA (511514), domestic cat HIRA (101098170), Horse HIRA (100052845), dog HIRA (486424) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(7290) Summary: This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
- Mouse(15260) histone cell cycle regulation defective homolog A (S. cerevisiae)
- Rat(363849) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Thale Cress(823578) protein HIRA
- Domestic Rabbit(100352472) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- sheep(101120607) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- cow(511514) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- domestic cat(101098170) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Horse(100052845) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- dog(486424) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- Zebrafish(568076) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- chicken(374074) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
- fruit fly(31680) CG12153 gene product from transcript CG12153-RA
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anty-HIRA, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot
western blot
Anty-HIRA, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-HIRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Przeciwciało anty-HIRA, klon WC119, clone WC119, from mouse,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunoprecipitation (IP)
western blot
western blot
Anti-HIRA antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
western blot