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Merck

HIRA

histone cell cycle regulator

Synonymes:
DGCR1, TUP1, TUPLE1
Espèce(s):
Human HIRA (7290), Mouse Hira (15260), Rat Hira (363849), Thale Cress HIRA (823578), Domestic Rabbit HIRA (100352472), sheep HIRA (101120607), cow HIRA (511514), domestic cat HIRA (101098170), Horse HIRA (100052845), dog HIRA (486424) ...Plus
ID UniProtKB:
P54198, Q05BU9, Q8IXN2
ID du gène:
  • Human(7290) Summary: This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
  • Mouse(15260) histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Rat(363849) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Thale Cress(823578) protein HIRA
  • Domestic Rabbit(100352472) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • sheep(101120607) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • cow(511514) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • domestic cat(101098170) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Horse(100052845) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • dog(486424) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Zebrafish(568076) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • chicken(374074) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • fruit fly(31680) CG12153 gene product from transcript CG12153-RA

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Antibodies

Numéro du produit
Description
Espèces réactives
Application
04-1488
Anticorps anti-HIRA, clone WC119, clone WC119, from mouse,
Espèces réactives
human, mouse
Application
immunoprecipitation (IP)
western blot
HPA050714
Anti-HIRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
HPA052902
Anti-HIRA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Espèces réactives
human
Application
immunofluorescence
SAB1400286
Anti-HIRA antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
human
Application
immunofluorescence
western blot
SAB5702629
Anti-HIRA Antibody, clone 6Q7Y6, Rabbit Monoclonal, ,
Espèces réactives
human
Application
western blot

esiRNA

Numéro du produit
Description
Espèce(s)
EMU032731
MISSION® esiRNA, targeting mouse Hira,
Espèce(s)
mouse
EHU061801
MISSION® esiRNA, targeting human HIRA, C22ORF39,
Espèce(s)
human