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Merck

IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1

Sinónimos:
IMPD, IMPD1, LCA11, RP10, sWSS2608
Especie:
ID UniProtKB:
ID del gen:
  • Human(3614) Summary: The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
  • Mouse(23917) inosine 5'-phosphate dehydrogenase 1
  • Rat(362329) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Domestic Rabbit(100357217) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • dog(608783) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic guinea pig(100717020) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • naked mole-rat(101720344) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • domestic cat(101084274) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • Horse(100071737) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • sheep(101104144) IMP (inosine 5'-monophosphate) dehydrogenase 1
  • cow(504305) IMP (inosine 5'-monophosphate) dehydrogenase 1

Custom & Knockdown Gene Products

Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-IMPDH1 Antibody, clone 4F9.1, clone 4F9.1, from mouse,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Small Molecule - Inhibitor

Número de producto
Descripción
Especie
Ribavirin, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Ribavirin impurity standard, British Pharmacopoeia (BP) Reference Standard,
Especie
human
Ribavirin, British Pharmacopoeia (BP) Reference Standard,
Especie
human
6-Thioguanine, ≥98%,
Especie
human
Mycophenolic acid, ≥98%,
Especie
human

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting human IMPDH1,
Especie
human
MISSION® esiRNA, targeting mouse Impdh1,
Especie
mouse