LMNA
lamin A/C
Synonyme:
CDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, PRO1
Spezies:
Human LMNA (4000), Mouse Lmna (16905), Rat Lmna (60374), domestic guinea pig Lmna (100735212), chicken LMNA (415464), sheep LMNA (101107924), cow LMNA (404144), domestic cat LMNA (101086199), Horse LMNA (100057663), dog LMNA (480124) ...Mehr
UniProtKB-ID:
Gen-ID:
- Human(4000) Summary: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
- Mouse(16905) lamin A
- Rat(60374) lamin A/C
- domestic guinea pig(100735212) lamin A/C
- chicken(415464) lamin A/C
- sheep(101107924) lamin A/C
- cow(404144) lamin A/C
- domestic cat(101086199) lamin A/C
- Horse(100057663) lamin A/C
- dog(480124) lamin A/C
- Zebrafish(195815) lamin A
- naked mole-rat(101704567) lamin A/C
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Antibodies
Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-prelamin A Antibody, clone PL-1C7, clone PL-1C7, from mouse,
Speziesreaktivität
human, mouse
Anwendung
ELISA
flow cytometry
immunocytochemistry
western blot
flow cytometry
immunocytochemistry
western blot
Anti-Progerin antibody, Mouse monoclonal, clone 13A4, purified from hybridoma cell culture,
Speziesreaktivität
human
Anwendung
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Progerin-Antikörper, Klon 13A4, clone 13A4, Upstate®, from mouse,
Speziesreaktivität
human
Anwendung
ELISA
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Anti-Lamin A/C Antibody, clone 4C11, clone 4C11, from mouse,
Speziesreaktivität
syrian hamster, human, monkey, mouse, rat
Anwendung
ChIP
immunofluorescence
immunoprecipitation (IP)
western blot
immunofluorescence
immunoprecipitation (IP)
western blot
Anti-LMNA antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
western blot
western blot