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MEP1B

meprin A, beta

Synonymes:
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4225) Summary: Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine. [provided by RefSeq, Oct 2011]
  • Mouse(17288) meprin 1 beta
  • Rat(25727) meprin 1 beta
  • cow(540701) meprin A, beta
  • Zebrafish(100151009) meprin A, beta
  • domestic cat(101089149) meprin A, beta
  • Horse(100052389) meprin A, beta
  • domestic guinea pig(100733995) meprin A, beta
  • dog(490497) meprin A, beta
  • naked mole-rat(101721966) meprin A, beta
  • sheep(101114072) meprin A, beta
  • chicken(421097) meprin A, beta
  • Domestic Rabbit(100349918) meprin A, beta

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human Meprin beta ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-MEP1B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MEP1B,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Mep1b,
Espèce(s)
mouse