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MMP11

matrix metallopeptidase 11 (stromelysin 3)

Synonyme:
SL-3, ST3, STMY3
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(4320) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
  • Mouse(17385) matrix metallopeptidase 11
  • Rat(25481) matrix metallopeptidase 11
  • sheep(101110364) matrix metallopeptidase 11 (stromelysin 3)
  • Horse(100056568) matrix metallopeptidase 11 (stromelysin 3)
  • dog(486408) matrix metallopeptidase 11 (stromelysin 3)
  • chicken(769489) matrix metallopeptidase 11 (stromelysin 3)
  • domestic cat(101089148) matrix metallopeptidase 11 (stromelysin 3)
  • naked mole-rat(101699533) matrix metallopeptidase 11 (stromelysin 3)
  • cow(539109) matrix metallopeptidase 11 (stromelysin 3)
  • domestic guinea pig(100713229) matrix metallopeptidase 11 (stromelysin 3)

Custom & Knockdown Gene Products

Antibodies

Produktnummer
Beschreibung
Speziesreaktivität
Anwendung
Anti-MMP-11 (Stromelysin-3) Antibody, clone 5ST-4A9, clone 5ST-4A9, from mouse,
Speziesreaktivität
human
Anwendung
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MMP11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunohistochemistry
Anti-Mmp11 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Speziesreaktivität
human
Anwendung
immunofluorescence

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Marimastat, ≥98% (HPLC),
Spezies
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Spezies
human, rat, mouse

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human MMP11, AP000349.2,
Spezies
human
MISSION® esiRNA, targeting mouse Mmp11,
Spezies
mouse