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Merck

MMP11

matrix metallopeptidase 11 (stromelysin 3)

Sinonimi:
SL-3, ST3, STMY3
Specie:
ID UniProtKB:
ID gene:
  • Human(4320) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq, Jul 2008]
  • Mouse(17385) matrix metallopeptidase 11
  • Rat(25481) matrix metallopeptidase 11
  • sheep(101110364) matrix metallopeptidase 11 (stromelysin 3)
  • Horse(100056568) matrix metallopeptidase 11 (stromelysin 3)
  • dog(486408) matrix metallopeptidase 11 (stromelysin 3)
  • chicken(769489) matrix metallopeptidase 11 (stromelysin 3)
  • domestic cat(101089148) matrix metallopeptidase 11 (stromelysin 3)
  • naked mole-rat(101699533) matrix metallopeptidase 11 (stromelysin 3)
  • cow(539109) matrix metallopeptidase 11 (stromelysin 3)
  • domestic guinea pig(100713229) matrix metallopeptidase 11 (stromelysin 3)

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-MMP-11 (Stromelysin-3) Antibody, clone 5ST-4A9, clone 5ST-4A9, from mouse,
Reattività con
human
Applicazione
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MMP11 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
Anti-Mmp11 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence

Small Molecule - Inhibitor

Numero di prodotto
Descrizione
Specie
Marimastat, ≥98% (HPLC),
Specie
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Specie
human, rat, mouse

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human MMP11, AP000349.2,
Specie
human
MISSION® esiRNA, targeting mouse Mmp11,
Specie
mouse