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Merck

MMP15

matrix metallopeptidase 15 (membrane-inserted)

Synonymes:
MT2-MMP, MTMMP2, SMCP-2
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4324) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq, Jul 2008]
  • Mouse(17388) matrix metallopeptidase 15
  • Rat(291848) matrix metallopeptidase 15
  • dog(487257) matrix metallopeptidase 15 (membrane-inserted)
  • Horse(100062872) matrix metallopeptidase 15 (membrane-inserted)
  • naked mole-rat(101718286) matrix metallopeptidase 15 (membrane-inserted)
  • domestic guinea pig(100720154) matrix metallopeptidase 15 (membrane-inserted)
  • sheep(101122213) matrix metallopeptidase 15 (membrane-inserted)
  • cow(282887) matrix metallopeptidase 15 (membrane-inserted)
  • Domestic Rabbit(100347975) matrix metallopeptidase 15 (membrane-inserted)
  • chicken(415629) matrix metallopeptidase 15 (membrane-inserted)
  • domestic cat(101088040) matrix metallopeptidase 15 (membrane-inserted)

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-MMP15 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-MMP-15 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse
Application
ELISA
western blot
Anti-MMP15 (Cleaved-Tyr132) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
western blot

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
Marimastat, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Espèce(s)
human, rat, mouse

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MMP15,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Mmp15,
Espèce(s)
mouse