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MMP20

matrix metallopeptidase 20

Synonyme:
AI2A2, MMP-20
Spezies:
UniProtKB-ID:
Gen-ID:
  • Human(9313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene degrades amelogenin, the major protein component of dental enamel matrix, and thus thought to play a role in tooth enamel formation. A mutation in this gene, which alters the normal splice pattern and results in premature termination of the encoded protein, has been associated with amelogenesis imperfecta. This gene is part of a cluster of MMP genes located on chromosome 11q22.3. [provided by RefSeq, Aug 2011]
  • Mouse(30800) matrix metallopeptidase 20 (enamelysin)
  • Rat(300341) matrix metallopeptidase 20
  • cow(281916) matrix metallopeptidase 20
  • sheep(101119666) matrix metallopeptidase 20
  • domestic cat(101080734) matrix metallopeptidase 20
  • domestic guinea pig(100719984) matrix metallopeptidase 20
  • naked mole-rat(101717548) matrix metallopeptidase 20
  • dog(611829) matrix metallopeptidase 20

Custom & Knockdown Gene Products

Small Molecule - Inhibitor

Produktnummer
Beschreibung
Spezies
Marimastat, ≥98% (HPLC),
Spezies
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Spezies
human, rat, mouse

esiRNA

Produktnummer
Beschreibung
Spezies
MISSION® esiRNA, targeting human MMP20,
Spezies
human