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Merck

MMP9

matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

Synonymes:
CLG4B, GELB, MANDP2, MMP-9
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(4318) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]
  • Mouse(17395) matrix metallopeptidase 9
  • Rat(81687) matrix metallopeptidase 9
  • Domestic Rabbit(100008993) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • sheep(100192422) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • dog(403885) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • domestic cat(101084185) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • cow(282871) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • domestic guinea pig(100728510) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • chicken(395387) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • Horse(100169862) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • naked mole-rat(101717243) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
  • Zebrafish(406397) matrix metalloproteinase 9
  • Horse(100056599) matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human MMP-9 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Espèce(s)
human
Mouse pro-MMP-9 ELISA Kit, for serum, plasma and cell culture supernatant,
Espèce(s)
mouse
Rabbit MMP-9 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Espèce(s)
domestic rabbit
Rhesus Macaque MMP-9 ELISA, for serum, plasma and cell culture supernatants,
Espèce(s)
rat

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-Métalloprotéinase matricielle-9 antibody produced in goat, affinity isolated antibody,
Espèces réactives
mouse
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anticorps anti-MMP-9, domaine catalytique, Chemicon®, from rabbit,
Espèces réactives
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-MMP9 antibody produced in rabbit, IgG fraction of antiserum,
Espèces réactives
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
immunohistochemistry
western blot
Anti-MMP-9 (Ab-1) Mouse mAb (6-6B), lyophilized, clone 6-6B, Calbiochem®,
Espèces réactives
human
Application
Anti-MMP9 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
α-Sexithiophene, ,
Espèce(s)
human, rat
Marimastat, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
CP-101537, ≥98% (HPLC),
Espèce(s)
human, rat, mouse
PD166793 hydrate, ≥98% (HPLC),
Espèce(s)
human, rat, mouse

Proteins

Numéro du produit
Description
Espèce(s)
Matrix Metalloproteinase-9 human, recombinant, >90% (SDS-PAGE), buffered aqueous solution,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human MMP9,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Mmp9,
Espèce(s)
mouse