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Merck

NEFL

neurofilament, light polypeptide

Sinonimi:
CMT1F, CMT2E, NF-L, NF68, NFL
Specie:
ID UniProtKB:
ID gene:
  • Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
  • Mouse(18039) neurofilament, light polypeptide
  • Rat(83613) neurofilament, light polypeptide
  • chicken(419528) neurofilament, light polypeptide
  • sheep(101119539) neurofilament, light polypeptide
  • cow(281348) neurofilament, light polypeptide
  • dog(477378) neurofilament, light polypeptide
  • naked mole-rat(101704332) neurofilament, light polypeptide
  • domestic cat(101081039) neurofilament, light polypeptide
  • domestic guinea pig(100731797) neurofilament, light polypeptide

Custom & Knockdown Gene Products

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anticorpo anti-neurofilamento L, serum, Chemicon®,
Reattività con
bovine, canine, feline, human, mouse, pig, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Monoclonal Anti-Neurofilament 68 antibody produced in mouse, clone NR4, ascites fluid,
Reattività con
chicken, human, pig, rat
Applicazione
immunohistochemistry
microarray

western blot
Anticorpo anti-neurofilamento di 70 kDa, clone DA2, culture supernatant, clone DA2, Chemicon®,
Reattività con
bovine, human, mouse, pig, rat
Applicazione
immunocytochemistry
immunohistochemistry

western blot
Anti-Neurofilament L Antibody, clone 1E13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human
Applicazione
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-phospho-NFL (Ser473) Antibody, clone 4F8, clone 4F8, from mouse,
Reattività con
bovine, human, mouse, porcine, rat, rhesus macaque
Applicazione
immunohistochemistry
western blot

Proteins

Numero di prodotto
Descrizione
Specie
Neurofilament 70 kDa, porcine, ,
Specie

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human NEFL,
Specie
human