NEFL
neurofilament, light polypeptide
Synonyms:
CMT1F, CMT2E, NF-L, NF68, NFL
Species:
Human NEFL (4747), Mouse Nefl (18039), Rat Nefl (83613), chicken NEFL (419528), sheep NEFL (101119539), cow NEFL (281348), dog NEFL (477378), naked mole-rat Nefl (101704332), domestic cat NEFL (101081039), domestic guinea pig Nefl (100731797)
UniProtKB ID:
Gene ID:
- Human(4747) Summary: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. [provided by RefSeq, Oct 2008]
- Mouse(18039) neurofilament, light polypeptide
- Rat(83613) neurofilament, light polypeptide
- chicken(419528) neurofilament, light polypeptide
- sheep(101119539) neurofilament, light polypeptide
- cow(281348) neurofilament, light polypeptide
- dog(477378) neurofilament, light polypeptide
- naked mole-rat(101704332) neurofilament, light polypeptide
- domestic cat(101081039) neurofilament, light polypeptide
- domestic guinea pig(100731797) neurofilament, light polypeptide
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NEFL antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Neurofilament L Antibody, clone 3L9Y10, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
Neurofilament (EP79) Rabbit Monoclonal Primary Antibody, ,
Species Reactivity
human
Application
immunohistochemistry
Neurofilament (2F11) Mouse Monoclonal Antibody, ,
Species Reactivity
human
Application
immunohistochemistry
Monoclonal Anti-NEFL antibody produced in mouse, clone 2G10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
flow cytometry
immunofluorescence
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
esiRNA
Product Number
Description
Species