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Merck

NME1

NME/NM23 nucleoside diphosphate kinase 1

Synonyms:
AWD, GAAD, NB, NBS, NDKA, NDPK-A, NDPKA, NM23, NM23-H1
Species:
Human NME1 (4830), Mouse Nme1 (18102), Rat Nme1 (191575), domestic guinea pig Nme1 (100379567), chicken NME1 (422094), Domestic Rabbit NME1 (100533971), cow NME1 (404189), Horse NME1 (100533966), dog NME1 (476767), dog NME1 (480558)
UniProtKB ID:
P15531, Q6FGK3, Q86XQ2, Q9UDJ6
Gene ID:
  • Human(4830) Summary: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Jul 2008]
  • Mouse(18102) NME/NM23 nucleoside diphosphate kinase 1
  • Rat(191575) NME/NM23 nucleoside diphosphate kinase 1
  • domestic guinea pig(100379567) NME/NM23 nucleoside diphosphate kinase 1
  • chicken(422094) non-metastatic cells 1, protein (NM23A) expressed in
  • Domestic Rabbit(100533971) NME/NM23 nucleoside diphosphate kinase 1
  • cow(404189) non-metastatic cells 1, protein (NM23A) expressed in
  • Horse(100533966) NME/NM23 nucleoside diphosphate kinase 1
  • dog(476767) non-metastatic cells 1, protein (NM23A) expressed in
  • dog(480558) non-metastatic cells 1, protein (NM23A) expressed in

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB1306677
ANTI-NM23 (NME1)(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot