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Merck

PA2G4

proliferation-associated 2G4, 38kDa

Synonyms:
EBP1, HG4-1, p38-2G4
Species:
UniProtKB ID:
Gene ID:
  • Human(5036) Summary: This gene encodes an RNA-binding protein that is involved in growth regulation. This protein is present in pre-ribosomal ribonucleoprotein complexes and may be involved in ribosome assembly and the regulation of intermediate and late steps of rRNA processing. This protein can interact with the cytoplasmic domain of the ErbB3 receptor and may contribute to transducing growth regulatory signals. This protein is also a transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes through its interactions with histone deacetylases. This protein has been implicated in growth inhibition and the induction of differentiation of human cancer cells. Six pseudogenes, located on chromosomes 3, 6, 9, 18, 20 and X, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(18813) proliferation-associated 2G4
  • Rat(288778) proliferation-associated 2G4
  • domestic guinea pig(100712672) proliferation-associated 2G4, 38kDa
  • chicken(425279) proliferation-associated 2G4, 38kDa
  • dog(474396) proliferation-associated 2G4, 38kDa
  • sheep(101111702) proliferation-associated 2G4, 38kDa
  • cow(540272) proliferation-associated 2G4, 38kDa
  • Horse(100051912) proliferation-associated 2G4, 38kDa
  • domestic cat(101095110) proliferation-associated 2G4, 38kDa
  • naked mole-rat(101720506) proliferation-associated 2G4, 38kDa

Custom & Knockdown Gene Products

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PA2G4 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot