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Merck

PPP1R12B

protein phosphatase 1, regulatory subunit 12B

Synonyms:
MYPT2, PP1bp55
Species:
Human PPP1R12B (4660), Mouse Ppp1r12b (329251), Rat Ppp1r12b (304813), sheep PPP1R12B (101110859), Domestic Rabbit PPP1R12B (100356902), Horse PPP1R12B (100063928), naked mole-rat Ppp1r12b (101711489), domestic guinea pig Ppp1r12b (100729743), chicken PPP1R12B (395478), domestic cat PPP1R12B (101098766) ...More
UniProtKB ID:
O60237, A8MYF5, B7ZMN6, Q2TAI8, Q5T506, Q5VUK2, Q8N179, Q9HCB7
Gene ID:
  • Human(4660) Summary: Myosin phosphatase is a protein complex comprised of three subunits: a catalytic subunit (PP1c-delta, protein phosphatase 1, catalytic subunit delta), a large regulatory subunit (MYPT, myosin phosphatase target) and small regulatory subunit (sm-M20). Two isoforms of MYPT have been isolated--MYPT1 and MYPT2, the first of which is widely expressed, and the second of which may be specific to heart, skeletal muscle, and brain. Each of the MYPT isoforms functions to bind PP1c-delta and increase phosphatase activity. This locus encodes both MYTP2 and M20. Alternatively spliced transcript variants encoding different isoforms have been identified. Related pseudogenes have been defined on the Y chromosome. [provided by RefSeq, Oct 2011]
  • Mouse(329251) protein phosphatase 1, regulatory (inhibitor) subunit 12B
  • Rat(304813) protein phosphatase 1, regulatory subunit 12B
  • sheep(101110859) protein phosphatase 1, regulatory subunit 12B
  • Domestic Rabbit(100356902) protein phosphatase 1, regulatory subunit 12B
  • Horse(100063928) protein phosphatase 1, regulatory subunit 12B
  • naked mole-rat(101711489) protein phosphatase 1, regulatory subunit 12B
  • domestic guinea pig(100729743) protein phosphatase 1, regulatory subunit 12B
  • chicken(395478) protein phosphatase 1, regulatory subunit 12B
  • domestic cat(101098766) protein phosphatase 1, regulatory subunit 12B
  • cow(100337338) protein phosphatase 1, regulatory subunit 12B
  • dog(490230) protein phosphatase 1, regulatory subunit 12B

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB5701921
Anti-Phospho-PPP1R12A/PPP1R12B/PPP1R12C-T696 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot