PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
Sinónimos:
AMPK, HAMPKb
Especie:
Human PRKAB1 (5564), Mouse Prkab1 (19079), Rat Prkab1 (83803), Horse PRKAB1 (100034094), sheep PRKAB1 (101107899), chicken PRKAB1 (416986), domestic cat PRKAB1 (101094051), naked mole-rat Prkab1 (101705863), cow PRKAB1 (534107), domestic guinea pig Prkab1 (100719458)
ID UniProtKB:
ID del gen:
- Human(5564) Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex. [provided by RefSeq, Jul 2008]
- Mouse(19079) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- Rat(83803) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- Horse(100034094) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- sheep(101107899) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- chicken(416986) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- domestic cat(101094051) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- naked mole-rat(101705863) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- cow(534107) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- domestic guinea pig(100719458) protein kinase, AMP-activated, beta 1 non-catalytic subunit
- dog(486295) protein kinase, AMP-activated, beta 1 non-catalytic subunit
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-PRKAB1 Antibody, clone 2M11 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
chimpanzee, human, mouse
Aplicación
affinity binding assay
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PRKAB1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PRKAB1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-Phospho-AMPKβ1-S108 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-Phospho-AMPKβ1-S182 antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
western blot
Proteins
Número de producto
Descripción
Especie
AMPK (α1/β1/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
AMPK (α1/β1/γ3), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
esiRNA
Número de producto
Descripción
Especie