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Merck

PRKAG1

protein kinase, AMP-activated, gamma 1 non-catalytic subunit

Synonyma:
AMPKG
Druh:
ID sady UniProtKB:
ID genu:
  • Human(5571) Summary: The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(19082) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Rat(25520) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Zebrafish(406440) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • cow(282324) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • dog(486559) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • domestic cat(101094684) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Domestic Rabbit(100356542) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • Horse(100034096) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • chicken(429688) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • naked mole-rat(101721085) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • domestic guinea pig(100716757) protein kinase, AMP-activated, gamma 1 non-catalytic subunit
  • sheep(101103143) protein kinase, AMP-activated, gamma 1 non-catalytic subunit

Custom & Knockdown Gene Products

Antibodies

Číslo produktu
Popis
Druhová reaktivita
Aplikace
Anti-PRKAG1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Druhová reaktivita
human
Aplikace
immunofluorescence
Anti-PRKAG1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Druhová reaktivita
human
Aplikace
immunofluorescence
western blot
Anti-PRKAG1 (center) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Druhová reaktivita
human, mouse
Aplikace
ELISA
immunohistochemistry

western blot

Proteins

Číslo produktu
Popis
Druh
AMPK (α2/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Druh
human
AMPK (α1/β1/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Druh
human
AMPK (α1/β2/γ1), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Druh
human

esiRNA

Číslo produktu
Popis
Druh
MISSION® esiRNA, targeting human PRKAG1,
Druh
human
MISSION® esiRNA, targeting mouse Prkag1,
Druh
mouse