SMAD7
SMAD family member 7
Sinonimi:
CRCS3, MADH7, MADH8
Specie:
Human SMAD7 (4092), Mouse Smad7 (17131), Rat Smad7 (81516), dog SMAD7 (490570), domestic cat SMAD7 (101088277), Zebrafish smad7 (326282), chicken SMAD7 (429683), domestic guinea pig Smad7 (100717293), naked mole-rat Smad7 (101718588), sheep SMAD7 (443160) ...Più
ID UniProtKB:
ID gene:
- Human(4092) Summary: The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]
- Mouse(17131) SMAD family member 7
- Rat(81516) SMAD family member 7
- dog(490570) SMAD family member 7
- domestic cat(101088277) SMAD family member 7
- Zebrafish(326282) MAD, mothers against decapentaplegic homolog 7 (Drosophila)
- chicken(429683) SMAD family member 7
- domestic guinea pig(100717293) SMAD family member 7
- naked mole-rat(101718588) SMAD family member 7
- sheep(443160) SMAD family member 7
- Horse(100033853) SMAD family member 7
- cow(535916) SMAD family member 7
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numero di prodotto
Descrizione
Reattività con
Applicazione
Anti-SMAD7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-SMAD7 (N-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody, suitable for western blot: 2 μg/mL,
Reattività con
human
Applicazione
immunofluorescence
western blot
western blot
Anti-SMAD7 Antibody, clone 2D15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reattività con
human, mouse, rat
Applicazione
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-SMAD7 antibody produced in mouse, clone 4E1, purified immunoglobulin, buffered aqueous solution,
Reattività con
human
Applicazione
ELISA
western blot
western blot
Anti-SMAD7 antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Reattività con
bovine, human, monkey, mouse, rat
Applicazione
immunofluorescence
western blot
western blot
esiRNA
Numero di prodotto
Descrizione
Specie