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Merck

SORT1

sortilin 1

Sinonimi:
Gp95, LDLCQ6, NT3
Specie:
ID UniProtKB:
ID gene:
  • Human(6272) Summary: This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes; however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p; the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins. [provided by RefSeq, Jul 2008]
  • Mouse(20661) sortilin 1
  • Rat(83576) sortilin 1
  • cow(511591) sortilin 1
  • sheep(101104538) sortilin 1
  • domestic guinea pig(100718269) sortilin 1
  • dog(479915) sortilin 1
  • domestic cat(101090199) sortilin 1
  • Horse(100061385) sortilin 1
  • chicken(100858592) sortilin 1
  • naked mole-rat(101698000) sortilin 1

Custom & Knockdown Gene Products

ELISA

Numero di prodotto
Descrizione
Specie
Human Sortilin ELISA, for serum, plasma and cell culture supernatants,
Specie
human

Antibodies

Numero di prodotto
Descrizione
Reattività con
Applicazione
Anticorpo anti-sortilina, clone F11, clone F11, from mouse,
Reattività con
human, mouse
Applicazione
ELISA
immunocytochemistry

immunohistochemistry

western blot
Anti-SORT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reattività con
human
Applicazione
immunohistochemistry
western blot
Anti-Sortilin Antibody, serum, Chemicon®,
Reattività con
human, mouse, rat
Applicazione
immunohistochemistry
western blot
Monoclonal Anti-SORT1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL6528, purified immunoglobulin, buffered aqueous glycerol solution,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot
Anti-Sortilin Antibody, clone 4E3.1, clone 4E3.1, from mouse,
Reattività con
human, mouse
Applicazione
immunohistochemistry
western blot

esiRNA

Numero di prodotto
Descrizione
Specie
MISSION® esiRNA, targeting human SORT1,
Specie
human
MISSION® esiRNA, targeting mouse Sort1,
Specie
mouse