SPHK1
sphingosine kinase 1
Sinónimos:
SPHK
Especie:
Human SPHK1 (8877), Mouse Sphk1 (20698), Rat Sphk1 (170897), Thale Cress SPHK1 (828239), Horse SPHK1 (100058875), domestic cat SPHK1 (101084918), dog SPHK1 (483329), domestic guinea pig Sphk1 (100727266), naked mole-rat Sphk1 (101711606), chicken SPHK1 (427803) ...Más
ID UniProtKB:
ID del gen:
- Human(8877) Summary: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
- Mouse(20698) sphingosine kinase 1
- Rat(170897) sphingosine kinase 1
- Thale Cress(828239) sphingosine kinase 1
- Horse(100058875) sphingosine kinase 1
- domestic cat(101084918) sphingosine kinase 1
- dog(483329) sphingosine kinase 1
- domestic guinea pig(100727266) sphingosine kinase 1
- naked mole-rat(101711606) sphingosine kinase 1
- chicken(427803) sphingosine kinase 1
- cow(618605) sphingosine kinase 1
- sheep(101105263) sphingosine kinase 1
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Antibodies
Número de producto
Descripción
Reactividad de especies
Aplicación
Anti-SPHK1 Antibody, clone 2H5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human
Aplicación
affinity binding assay
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot