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SPHK1

sphingosine kinase 1

Synonimy:
SPHK
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(8877) Summary: The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  • Mouse(20698) sphingosine kinase 1
  • Rat(170897) sphingosine kinase 1
  • Thale Cress(828239) sphingosine kinase 1
  • Horse(100058875) sphingosine kinase 1
  • domestic cat(101084918) sphingosine kinase 1
  • dog(483329) sphingosine kinase 1
  • domestic guinea pig(100727266) sphingosine kinase 1
  • naked mole-rat(101711606) sphingosine kinase 1
  • chicken(427803) sphingosine kinase 1
  • cow(618605) sphingosine kinase 1
  • sheep(101105263) sphingosine kinase 1

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-SPHK1 antibody produced in mouse, clone 1D6, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-SPHK1 Antibody, clone 2H5 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
immunoprecipitation (IP)

western blot
Anti-SPHK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
bovine, canine, human, mouse, rat
Zastosowanie
ELISA
western blot

Proteins

Numer produktu
Opis
Gatunek
Sphingosine kinase 1a Active from mouse, recombinant, expressed in baculovirus, ≥70% (SDS-PAGE),
Gatunek
human
Sphingosine Kinase 1 human, aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human SPHK1,
Gatunek
human
MISSION® esiRNA, targeting mouse Sphk1,
Gatunek
mouse