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Merck

TBXAS1

thromboxane A synthase 1 (platelet)

Synonymes:
BDPLT14, CYP5, CYP5A1, GHOSAL, THAS, TS, TXAS, TXS
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(6916) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to thromboxane A2, a potent vasoconstrictor and inducer of platelet aggregation. The enzyme plays a role in several pathophysiological processes including hemostasis, cardiovascular disease, and stroke. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(21391) thromboxane A synthase 1, platelet
  • Rat(24886) thromboxane A synthase 1, platelet
  • Zebrafish(792041) thromboxane A synthase 1 (platelet, cytochrome P450, family 5, subfamily A)
  • cow(509326) thromboxane A synthase 1 (platelet)
  • domestic cat(101091097) thromboxane A synthase 1 (platelet)
  • Horse(100066198) thromboxane A synthase 1 (platelet)
  • dog(482771) thromboxane A synthase 1 (platelet)
  • domestic guinea pig(100719442) thromboxane A synthase 1 (platelet)
  • Domestic Rabbit(100339354) thromboxane A synthase 1 (platelet)
  • sheep(101111361) thromboxane A synthase 1 (platelet)
  • chicken(418101) thromboxane A synthase 1 (platelet)
  • naked mole-rat(101697368) thromboxane A synthase 1 (platelet)

Custom & Knockdown Gene Products

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-TBXAS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
western blot
Anti-TBXAS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-TBXAS1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry

Small Molecule - Inhibitor

Numéro du produit
Description
Espèce(s)
Nifedipine, ≥98% (HPLC), powder,
Espèce(s)
rat, mouse, human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human TBXAS1,
Espèce(s)
human