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TGIF1

TGFB-induced factor homeobox 1

Synonimy:
HPE4, TGIF
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(7050) Summary: The protein encoded by this gene is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Alternative splicing has been observed at this locus and multiple splice variants encoding distinct isoforms are described. [provided by RefSeq, Jul 2013]
  • Mouse(21815) TGFB-induced factor homeobox 1
  • Rat(316742) TGFB-induced factor homeobox 1
  • sheep(101105544) TGFB-induced factor homeobox 1
  • cow(510050) TGFB-induced factor homeobox 1
  • Zebrafish(321756) TGFB-induced factor homeobox 1
  • domestic cat(101084747) TGFB-induced factor homeobox 1
  • dog(490537) TGFB-induced factor homeobox 1
  • domestic guinea pig(100716233) TGFB-induced factor homeobox 1
  • chicken(396339) TGFB-induced factor homeobox 1
  • naked mole-rat(101698504) TGFB-induced factor homeobox 1

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-TGIF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ChIP
immunofluorescence

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Tgif1,
Gatunek
mouse
MISSION® esiRNA, targeting human TGIF1,
Gatunek
human