Accéder au contenu
MilliporeSigma

TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b

Synonymes:
CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(8795) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(21933) tumor necrosis factor receptor superfamily, member 10b
  • Rat(364420) tumor necrosis factor receptor superfamily, member 10b
  • chicken(373904) tumor necrosis factor receptor superfamily, member 10b
  • cow(784541) tumor necrosis factor receptor superfamily, member 10b
  • cow(282533) tumor necrosis factor receptor superfamily, member 10b
  • naked mole-rat(101697353) tumor necrosis factor receptor superfamily, member 10b

Custom & Knockdown Gene Products

ELISA

Numéro du produit
Description
Espèce(s)
Human TRAIL R2 ELISA Kit, for serum, plasma and cell culture supernatants,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-DR5/CD262 Antibody, clone 1B19 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human, mouse
Application
affinity binding assay
flow cytometry

immunocytochemistry

immunohistochemistry

western blot
Anti-DR5 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Espèces réactives
human, mouse
Application
ELISA
immunocytochemistry

western blot
Anti-DR5 Antibody, CT, Chemicon®, from rabbit,
Espèces réactives
human
Application
western blot
Monoclonal Anti-CD262-APC antibody produced in mouse, clone DR5-01-1,
Espèces réactives
Application
flow cytometry
Monoclonal Anti-CD262-PE antibody produced in mouse, clone DR5-01-1, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
flow cytometry

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human TNFRSF10B,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Tnfrsf10b,
Espèce(s)
mouse