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Merck

TNFSF14

tumor necrosis factor (ligand) superfamily, member 14

Synonimy:
CD258, HVEML, LIGHT, LTg, TR2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(8740) Summary: The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF14, which is a member of the tumor necrosis factor receptor superfamily, and which is also known as a herpesvirus entry mediator (HVEM). This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. This protein has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(50930) tumor necrosis factor (ligand) superfamily, member 14
  • Rat(301133) tumor necrosis factor (ligand) superfamily, member 14
  • domestic guinea pig(100725147) tumor necrosis factor (ligand) superfamily, member 14
  • dog(611306) tumor necrosis factor (ligand) superfamily, member 14
  • naked mole-rat(101725636) tumor necrosis factor (ligand) superfamily, member 14
  • cow(505521) tumor necrosis factor (ligand) superfamily, member 14
  • domestic cat(101096542) tumor necrosis factor (ligand) superfamily, member 14

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human LIGHT ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-TNFSF14 antibody produced in mouse, clone 4E3, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot

Proteins

Numer produktu
Opis
Gatunek
LIGHT from mouse, recombinant, expressed in E. coli, ≥96% (SDS-PAGE), ≥96% (HPLC), suitable for cell culture,
Gatunek
mouse

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human TNFSF14,
Gatunek
human