TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
Synonimy:
4-1BB-L, CD137L
Gatunek:
Human TNFSF9 (8744), Mouse Tnfsf9 (21950), Rat Tnfsf9 (353218), dog TNFSF9 (476729), domestic cat TNFSF9 (101087207), cow TNFSF9 (521748), sheep TNFSF9 (101108388), domestic guinea pig Tnfsf9 (101788800), naked mole-rat Tnfsf9 (101711392)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(8744) Summary: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction.[provided by RefSeq, Oct 2008]
- Mouse(21950) tumor necrosis factor (ligand) superfamily, member 9
- Rat(353218) tumor necrosis factor (ligand) superfamily, member 9
- dog(476729) tumor necrosis factor (ligand) superfamily, member 9
- domestic cat(101087207) tumor necrosis factor (ligand) superfamily, member 9
- cow(521748) tumor necrosis factor (ligand) superfamily, member 9
- sheep(101108388) tumor necrosis factor (ligand) superfamily, member 9
- domestic guinea pig(101788800) tumor necrosis factor (ligand) superfamily, member 9
- naked mole-rat(101711392) tumor necrosis factor (ligand) superfamily, member 9
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ELISA
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Gatunek
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-TNFSF9 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anty-TNFSF9, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Przeciwciało anty-4-1BBL/CD137L, klon 8E5D6, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Anti TNF Superfamily Member 9 Antibody, clone 24GB2375, Rabbit Monoclonal, clone 24GB2375, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
immunofluorescence
western blot
immunofluorescence
western blot
Proteins
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4-1BBL human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Gatunek
human
esiRNA
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