TNK1
tyrosine kinase, non-receptor, 1
別名:
Species:
Human TNK1 (8711), Mouse Tnk1 (83813), Rat Tnk1 (303247), dog TNK1 (489470), domestic guinea pig Tnk1 (100735628), naked mole-rat Tnk1 (101721050), Horse TNK1 (100061776), cow TNK1 (510356), domestic cat TNK1 (101096181), sheep TNK1 (101119833)
UniProtKB ID:
遺伝子ID:
- Human(8711) Summary: The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
- Mouse(83813) tyrosine kinase, non-receptor, 1
- Rat(303247) tyrosine kinase, non-receptor, 1
- dog(489470) tyrosine kinase, non-receptor, 1
- domestic guinea pig(100735628) tyrosine kinase, non-receptor, 1
- naked mole-rat(101721050) tyrosine kinase, non-receptor, 1
- Horse(100061776) tyrosine kinase, non-receptor, 1
- cow(510356) tyrosine kinase, non-receptor, 1
- domestic cat(101096181) tyrosine kinase, non-receptor, 1
- sheep(101119833) tyrosine kinase, non-receptor, 1
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