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Merck

TPO

thyroid peroxidase

同義詞:
MSA, TDH2A, TPX
物種:
UniProtKB ID:
基因 ID:
  • Human(7173) Summary: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
  • Mouse(22018) thyroid peroxidase
  • Rat(54314) thyroid peroxidase
  • chicken(776120) thyroid peroxidase
  • domestic cat(101098706) thyroid peroxidase
  • dog(403521) thyroid peroxidase
  • cow(525013) thyroid peroxidase
  • domestic guinea pig(100723704) thyroid peroxidase
  • naked mole-rat(101704548) thyroid peroxidase

Custom & Knockdown Gene Products

ELISA

產品編號
描述
物種
人TPO /甲状腺过氧化物酶ELISA试剂盒, for serum, plasma, cell culture supernatants and urine,
物種
human

Antibodies

產品編號
描述
物種活性
應用
Anti-TPO antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
human
應用
ELISA
immunohistochemistry

western blot
Anti-TPO antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
甲巯咪唑, analytical standard,
物種
human
甲巯咪唑, United States Pharmacopeia (USP) Reference Standard,
物種
human
甲巯咪唑, VETRANAL®, analytical standard,
物種
human
甲巯咪唑, European Pharmacopoeia (EP) Reference Standard,
物種
human
2-巯基-1-甲基咪唑, ≥99%,
物種
human

Proteins

產品編號
描述
物種
血小板生成素, TPO (Thrombopoietin, Mpl-ligand, MGDF) stimulates the proliferation & maturation of megakaryocytes & promotes increased circulating levels of platelets in vivo.,
物種
human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting human TPO,
物種
human