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Merck

TRPV1

transient receptor potential cation channel, subfamily V, member 1

別名:
VR1
Species:
UniProtKB ID:
遺伝子ID:
  • Human(7442) Summary: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(193034) transient receptor potential cation channel, subfamily V, member 1
  • Rat(83810) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(101093406) transient receptor potential cation channel, subfamily V, member 1
  • chicken(395259) transient receptor potential cation channel, subfamily V, member 1
  • naked mole-rat(101720480) transient receptor potential cation channel, subfamily V, member 1
  • Domestic Rabbit(100008926) transient receptor potential cation channel, subfamily V, member 1
  • domestic cat(100303454) transient receptor potential cation channel, subfamily V, member 1
  • Zebrafish(561195) transient receptor potential cation channel, subfamily V, member 1
  • cow(539074) transient receptor potential cation channel, subfamily V, member 1
  • domestic guinea pig(100135466) transient receptor potential cation channel, subfamily V, member 1
  • Horse(100034158) transient receptor potential cation channel, subfamily V, member 1
  • sheep(101110158) transient receptor potential cation channel, subfamily V, member 1
  • dog(445457) transient receptor potential cation channel, subfamily V, member 1

Custom & Knockdown Gene Products

Small Molecule - Agonist

製品番号
詳細
Species
ジヒドロカプサイシン, from Capsicum sp., ≥85%,
Species
rat, human
N-オレオイルエタノールアミン, ~98% (TLC),
Species
human, mouse, rat

Small Molecule - Antagonist

製品番号
詳細
Species
SB-366791, ≥98% (HPLC), powder,
Species
human
6-Iodonordihydrocapsaicin, ≥98% (HPLC), solid,
Species
human
カプサゼピン, ≥98% (HPLC), solid,
Species
human, rat
カプサイシン, ≥95%, from Capsicum sp.,
Species
rat, human
カプサイシン, natural,
Species
rat, human

Antibodies

製品番号
詳細
交差性
アプリケーション
Anti-Capsaicin Receptor Antibody, CT, serum, Chemicon®,
交差性
rat
アプリケーション
immunohistochemistry
Anti-TRPV1 antibody produced in rabbit, ,
交差性
human, mouse, rat
アプリケーション
immunofluorescence
western blot
Anti-Capsaicin Receptor Antibody, NT, serum, Chemicon®,
交差性
mouse, primate, rat
アプリケーション
immunohistochemistry
western blot
Monoclonal Anti-TRPV1 antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
交差性
human
アプリケーション
ELISA
western blot
Anti-TRPV1 antibody produced in rabbit, affinity isolated antibody,
交差性
human
アプリケーション
ELISA
western blot

Small Molecule - Inhibitor

製品番号
詳細
Species
Olvanil, powder,
Species
human
アセトアミノフェン, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
カプサイシン, ≥95%, from Capsicum sp.,
Species
rat, human
アセトアミノフェン, United States Pharmacopeia (USP) Reference Standard,
Species
human
アセトアミノフェン, BioXtra, ≥99.0%,
Species
human

Small Molecule - Mixed Agonist/Antagonist

製品番号
詳細
Species
カプサゼピン, ≥98% (HPLC), solid,
Species
human, rat

Small Molecule - Opener

製品番号
詳細
Species
カプサイシン, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
カプサイシン, analytical standard,
Species
human
カプサイシン, United States Pharmacopeia (USP) Reference Standard,
Species
human
カプサイシン, phyproof® Reference Substance,
Species
human
カプサイシン, European Pharmacopoeia (EP) Reference Standard,
Species
human

Proteins

製品番号
詳細
Species
Capsaicin Receptor Control Peptide for AB5889, ,
Species
rat

esiRNA

製品番号
詳細
Species
MISSION® esiRNA, targeting human TRPV1,
Species
human
MISSION® esiRNA, targeting mouse Trpv1,
Species
mouse