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Merck

ZAK

Synonymes:
AZK, MLK7, MLT, MLTK, MRK, mlklak, pk
Espèce(s):
Human ZAK (51776), Mouse Zak (65964), Rat Zak (311743), chicken ZAK (424149), cow ZAK (519251), dog ZAK (478802)
ID UniProtKB:
ID du gène:
  • Human(51776) Summary: This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Mouse(65964) sterile alpha motif and leucine zipper containing kinase AZK
  • Rat(311743) sterile alpha motif and leucine zipper containing kinase AZK
  • chicken(424149) sterile alpha motif and leucine zipper containing kinase AZK
  • cow(519251) sterile alpha motif and leucine zipper containing kinase AZK
  • dog(478802) sterile alpha motif and leucine zipper containing kinase AZK

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Antibodies

Numéro du produit
Description
Espèces réactives
Application
WH0051776M2
Monoclonal Anti-ZAK antibody produced in mouse, clone 3D11, purified immunoglobulin, buffered aqueous solution,
Espèces réactives
human
Application
ELISA
immunofluorescence
western blot

Proteins

Numéro du produit
Description
Espèce(s)
SRP5101
ZAK, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Espèce(s)
human