Concerned About Supply Disruptions for TRIS?

Tris [tris(hydroxymethyl)aminomethane] is one of the most widely used biological buffer components in the life sciences. Ongoing supply issues with top Tris manufacturers/suppliers and market pressures have brought the future global supply of this key material into question. Supply disruptions in the marketplace due to unforeseen circumstances can have major impact on your ability to perform R&D and manufacture reagents and kits for use.

Without a secure supply of quality material, some Tris users could see delays from switching buffer systems or, even worse, experience a shutdown of production or quality issues.

 

 How can you prepare?

At this time of uncertainty, we highly recommend that all Tris users:

  1. Check  your use of Tris products and make certain that your supply is secure.
  2. Have a backup supplier qualified.  Also, confirm this supplier is capable of handling your future requirements.
  3. Consider alternative buffers for non-critical applications. Explore other product options using this interactive buffer selection guide.

 

 How can we help?

As a trusted provider of Tris under the Trizma® trademark for more than 55 years, we offer the broadest range of buffer products in the market that maintain consistent performance, on a global scale. Backed by unrivaled quality and supply chain systems, we make sure the materials you need are always available, at the right quality grade. To ensure that we maintain a consistent stock of Tris and its related components, we have worked with our suppliers of CRITICAL raw materials, and scaled up our manufacturing to meet the demands of our customers. Currently, the top 15 global IVD companies purchase raw materials from us and rely on our dual vendor qualification process and other stringent supply chain procedures to protect seamless development and manufacturing practices.

Links to our Tris products are listed below. Simply click on the product number and you will be directed to the product purchasing page. You may also contact us directly or learn more about our supply chain and quality management systems.

 

CAS No. Product No. Description
77-86-1 T1378 Sigma 7-9®, ≥99% (titration), crystalline
77-86-1 T1503 Trizma® base, Primary Standard and Buffer, ≥99.9% (titration), crystalline
77-86-1 T4661 Trizma® base, ≥99.9% (titration), crystalline
77-86-1 T6066 Trizma® base, BioPerformance Certified, meets EP, USP testing specifications, cell culture tested, ≥99.9% (titration)
77-86-1 T6791 Trizma® base, BioXtra, pH 10.5-12.0 (1 M in H2O), ≥99.9% (titration)
77-86-1 93362 Trizma® base, BioUltra, for molecular biology, ≥99.8% (T)
77-86-1 RDD008 Trizma® base, anhydrous, free-flowing, Redi-Dri™, ≥99.9%
77-86-1 RES3137T Tromethamine, PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture, meets USP testing specifications
77-86-1 RES3193T Tromethamine, PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture, Meets USP, EP, JPC, BP testing specifications.
77-86-1 93350 Trizma® base, puriss. p.a., ≥99.7% (T)
77-86-1 93352 Trizma® base, ≥99.0% (T)
1185-53-1 T3253 Trizma® hydrochloride, reagent grade, ≥99.0% (titration), crystalline
1185-53-1 T5941 Trizma® hydrochloride, BioPerformance Certified, cell culture tested, ≥99.0% (titration)
1185-53-1 T6666 Trizma® hydrochloride, pH 3.5-5.0 (0.5 M in H2O), BioXtra, ≥99.0% (titration)
1185-53-1 93363 Trizma® hydrochloride, BioUltra, for molecular biology, ≥99.0% (AT)
1185-53-1 RDD009 Trizma® hydrochloride, anhydrous, free-flowing, Redi-Dri™, ≥99.0%
1185-53-1 PHG0002 TRIS hydrochloride, PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production, suitable for cell culture
1185-53-1 RES3098T TRIS hydrochloride, PharmaGrade, Manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production., suitable for cell culture
1185-53-1 648313 Tris, Hydrochloride, ULTROL® Grade
1185-53-1 648317 Tris, Hydrochloride, Molecular Biology Grade - Calbiochem
1185-53-1 9310-OP OmniPur® TRIS Hydrochloride - Calbiochem