3D Cell Culture Products

Sigma® offers a broad portfolio of three-dimensional cell culture systems, including products for creating Spheroids, Cell Culture Scaffolds, and Bioreactors. These products provide three-dimensional environments in which cells are better able to mimic their in vivo counterparts.

3-D cell culture models are a more accurate representation of the natural environment experienced by the cells in the living organism as opposed to growing cells on flat surfaces. Reflecting natural conditions allows for intercellular interactions with more realistic biochemical and physiological responses. In a 3-D environment, cells behave and respond more like they would in vivo to internal and external stimuli, such as changes in temperature, pH, nutrient absorption, transport, and differentiation. The only way to understand these fascinating processes in biology is to study model systems that truly resemble those in the organism, making 3-D cell culture imperative.